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The Pierfranco and Luisa Mariani Foundation was established on 18 June 1984 by Luisa Toffoloni Mariani in memory of her husband, a well-known businessman from Milan. The Foundation is a non-profit organization with legal status, its registered offices are in Milan, and it was granted legal recognition at national level.

Its core mission is child neurology and the major areas of expertise include:
• Services
• Training
• Research

The Statute singles out the “Carlo Besta” Neurological Institute of Milan as the privileged partner of the Foundation for its activities of training and project management and implementation.

Transparency, subsidiarity, efficiency, and effectiveness are the fundamental principles underlying the whole range of actions taken by the Mariani Foundation.